Vehicular communications at high frequencies are envisioned to be a breakthrough application for the 6G cellular systems. Traditional Radio Access Networks (RANs) lack the flexibility to enable sophisticated control mechanisms that are demanded by the strict performance requirements of the dynamic vehicular environment. In contrast, the features of Open RAN (O-RAN) can be exploited to support advanced use cases. Indeed, the emerging paradigm of O-RAN represents an ideal framework for the orchestration of vehicular communication. Although the high potential stemming from their integration can be easily seen and recognized, the effective combination of the two ecosystems is an open issue. This article pioneers the integration of the two strategies for seamlessly incorporating vehicle-to-everything (V2X) control within O-RAN's ecosystem. We propose and discuss an enabling architecture that tightly integrates V2X and O-RAN. In the proposed solution, an O-RAN-based control plane operates at low frequencies to achieve reliable and efficient connectivity among autonomous vehicles at higher frequencies. The technological feasibility of this integrated architecture is investigated. A detailed case study is presented and analyzed to demonstrate the design of an xApp to showcase a practical example of O-RAN solution for a specific V2X scenario.

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