The widespread adoption of data-centric algorithms, particularly Artificial Intelligence (AI) and Machine Learning (ML), has exposed the limitations of centralized processing infrastructures, driving a shift towards edge computing. This necessitates stringent constraints on energy efficiency, which traditional von Neumann architectures struggle to meet. The Compute-In-Memory (CIM) paradigm has emerged as a superior candidate due to its efficient exploitation of available memory bandwidth. However, existing CIM solutions require high implementation effort and lack flexibility from a software integration standpoint. This work proposes a novel, software-friendly, general-purpose, and low-integration-effort Near-Memory Computing (NMC) approach, paving the way for the adoption of CIM-based systems in the next generation of edge computing nodes. Two architectural variants, NM-Caesar and NM-Carus, are proposed and characterized to target different trade-offs in area efficiency, performance, and flexibility, covering a wide range of embedded microcontrollers. Post-layout simulations show up to $25.8\times$ and $50.0\times$ lower execution time and $23.2\times$ and $33.1\times$ higher energy efficiency at the system level, respectively, compared to executing the same tasks on a state-of-the-art RISC-V CPU (RV32IMC). NM-Carus achieves a peak energy efficiency of $306.7$ GOPS/W in 8-bit matrix multiplications, surpassing recent state-of-the-art in- and near-memory circuits.

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