This paper presents an in-depth analysis of timing closure challenges and constraints in Field Programmable Gate Arrays (FPGAs) and Application Specific Integrated Circuits (ASICs). We examine core timing principles, architectural distinctions, and design methodologies influencing timing behavior in both technologies. A case study comparing the Xilinx Kintex UltraScale+ FPGA (XCKU040) with a 7nm ASIC highlights practical timing analysis and performance trade-offs. Experimental results show ASICs achieve superior timing of 45ps setup and 35ps hold, while modern FPGAs remain competitive with 180ps setup and 120ps hold times, validating their suitability for high-performance designs.

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