Prompt optimization has emerged as an effective alternative to retraining for improving the performance of Large Language Models (LLMs). However, most existing approaches treat evaluation as a black box, relying solely on numerical scores while offering limited insight into why a prompt succeeds or fails. They also depend heavily on trial-and-error refinements, which are difficult to interpret and control. In this paper, we introduce MA-SAPO, a Multi-Agent framework for Score-Aware Prompt Optimization. Compared to prior methods, MA-SAPO explicitly couples evaluation outcomes with structured reasoning to guide systematic edits. The framework specifically consists of two stages: during the Reasoning Phase, agents collaboratively explain metric scores, diagnose weaknesses, and synthesize targeted refinements that are stored as reusable reasoning assets; during the Test Phase, agents retrieve these assets to analyze optimized prompts and apply only evidence-grounded edits. By turning evaluation signals into interpretable reasoning chains, MA-SAPO produces prompt refinements that are more transparent, auditable, and controllable. Experiments on the HelpSteer1/2 benchmarks demonstrate consistent improvements over single-pass prompting, retrieval-augmented baselines, and prior multi-agent strategies, validating the effectiveness of our approach.

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