Artificial intelligence (AI) is already driving scientific breakthroughs in a variety of research fields, ranging from the life sciences to mathematics. This raises a critical question: can AI be applied both responsibly and effectively to address complex and interconnected sustainability challenges? This report is the result of a collaboration between the Stockholm resilience Centre (Stockholm University), the Potsdam Institute for Climate Impact Research (PIK), and Google DeepMind. Our work explores the potential and limitations of using AI as a research method to help tackle eight broad sustainability challenges. The results build on iterated expert dialogues and assessments, a systematic AI-supported literature overview including over 8,500 academic publications, and expert deep-dives into eight specific issue areas. The report also includes recommendations to sustainability scientists, research funders, the private sector, and philanthropies.

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